Scientists Crack the Code for Mapping Gene Activity Across Whole Transplanted Limbs
Researchers at the University of Freiburg have developed the first optimized workflow for spatial transcriptomics and immunofluorescence on whole rat ...
Tag: Spatial transcriptomics
Scientists Pinpoint the Moment Stress Turns Into Depression in the Brain
A new Nature Neuroscience study maps a precisely timed, seven-day window in which chronic stress remodels the mouse lateral habenula ...
Scientists Map the Hidden Cellular Wiring That Drives Rheumatoid Arthritis Joint Destruction
A cross-species single-cell and spatial transcriptomics study reveals a conserved Notch/AP-1 to fibronectin and thrombospondin signaling axis operating in a ...
Ancient somatosensory circuit architectures employ flexible molecular strategies
A study of little skate embryos reveals that the layered spinal cord and target-dependent maturation of touch and pain circuits ...
Fibroblast collagen signal drives gut scarring and cancer in inflammatory bowel disease
A single-nuclei study reveals how CXCL14+ fibroblasts and SPP1+ macrophages form a collagen IV-driven feedback loop that promotes fibrosis and ...
Myeloid IL6/STAT3 Signaling Builds Immunosuppressive Niche That Fuels Colitis-Linked Cancer
Multi-omics study reveals how myeloid-derived IL6/JAK/STAT3 signaling creates a spatially organized immunosuppressive niche that drives colitis-associated carcinogenesis, offering a potential ...
Single-Cell Sequencing Reveals Why Diabetic Foot Ulcers Refuse to Heal
A new review details how single-cell RNA sequencing is exposing the cellular and molecular failures that keep diabetic foot ulcers ...
Enhanced Recovery Care Reshapes Immune Response After Bladder Cancer Surgery
A retrospective study of 126 bladder cancer patients suggests that ERAS-based perioperative nursing care is associated with gentler postoperative immune ...
Scientists Map the Cellular Ecosystem That Drives Liver Cancer Spread Through Blood Vessels
Single-cell RNA sequencing of hepatocellular carcinoma reveals that MRC1-positive macrophages, endothelial capillarization, and strengthened PTPRM signaling define the tumor ecosystem ...
How Persistent HPV Infection Drives Cervical Precancer: Molecular Pathways, Immune Evasion and Emerging Technologies
A new review in Cellular and Molecular Life Sciences maps the molecular pathways, immune microenvironment and AI-driven technologies that shape ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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