Genetic and cell studies point to miR-539-3p–SOX9 pattern in keloids
A multi-method study prioritized miR-539-3p and SOX9 as linked candidates in keloid tissue and fibroblasts, while leaving their regulatory relationship ...
Tag: SOX9
Red Light Before Implantation Primes Stem Cell Mitochondria to Rebuild Tracheal Cartilage
Preconditioning stem cells with a defined dose of 660 nm red light reprograms their mitochondria and activates a SOX9-driven chondrogenic ...
Cancer Cells Turn Fat Factories: SOX9 Fuels Colorectal Cancer Spread Through Lipid Rewiring
New research reveals that the transcription factor SOX9 drives colorectal cancer metastasis by directly activating the fat-synthesizing enzyme FASN, and ...
Single-Cell Atlas Reveals How Goat Embryos Turn Intersex, Offering Clues to Human Sex Development
Single-cell RNA sequencing of dairy goat embryos has revealed how stromal and epithelial cells steer gonad development and which genes, ...
Hidden Genetic Switch Links Cleft Lip Risk Gene to Neural Crest Cells
New research shows that the cleft lip and palate risk gene IRF6 is directly controlled by the transcription factor SOX9 ...
Immune Cells Hand Esophageal Cancer Its Stem-Like Edge Through an HNF1A/CXCL1 Circuit
New research shows that myeloid-derived suppressor cells drive stem-like properties in esophageal squamous cell carcinoma through an IL-1 beta-regulated HNF1A/CXCL1 ...
SOX9 Acts Early to Rewire Hippo–YAP/TAZ Signaling as Glioblastoma Cells Turn Stem-Like
New research shows that the transcription factor SOX9 primes Hippo–YAP/TAZ pathway rewiring during a narrow early window of stemness acquisition ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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