FDA-Approved RNA Drugs Show Mostly Mild Side Effects, But Long-Term Safety Data Remain Thin
A new cross-platform review of eighteen FDA-approved RNA therapeutics finds that adverse effects depend more on delivery chemistry and administration ...
Tag: siRNA
EGFR Co-Targeting with Nanocarriers Offers New Precision Path for Triple-Negative Breast Cancer
A new review in Genes & Diseases outlines how co-targeting EGFR alongside other tumor-driving molecules, delivered via nanocarriers, could enable ...
Tiny Metal Machines: How Inorganic Nanoparticles Are Rewriting Targeted Cancer Therapy
A new review in Pharmacia charts how magnetic nanoparticles, metal-organic frameworks, and ROS-responsive carriers are transforming targeted cancer therapy and ...
Why siRNA Delivery Keeps Failing in Neurodegenerative Diseases
A new review argues that the bottleneck for RNAi therapies in Alzheimer's, Parkinson's and Huntington's disease is not gene silencing ...
Cataract Clouding in Diabetes Traced to a DNA-Sensing Inflammatory Chain Reaction
Researchers at Sun Yat-sen University show that blocking the cGAS-STING pathway and the NLRP3 inflammasome reduces inflammatory cell death and ...
AI Steps Into RNA Drug Discovery, From Small Molecules to Oligonucleotide Therapeutics
A new review maps how artificial intelligence is transforming RNA-targeted drug discovery across both small molecules and oligonucleotide therapeutics.
Silencing a Fat-Making Master Switch Pushes Pancreatic Cancer Cells Toward Self-Destruction
New research links elevated SREBF1 expression to lipid metabolism signatures in pancreatic cancer and shows that silencing the gene triggers ...
Estrogen Receptor Gene ESR1 Emerges as a Master Switch for Buffalo Milk Production
New research shows that the estrogen receptor gene ESR1 promotes milk fat and protein synthesis, cell proliferation, and survival in ...
Silencing HPV16 Oncogenes E5 and E6 Emerges as a Promising Route Against Cervical Cancer
A new review in Virology Journal examines how siRNA and CRISPR/Cas gene-silencing technologies could target the HPV16 oncoproteins E5 and ...
Cellular Recycling Machine Linked to Male Fertility Hormone Control
New research reveals that the cellular recycling protein p97/VCP directly regulates the autophagic degradation of androgen-binding protein in Sertoli cells, ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!