Single-Cell Atlas of Glioma Reveals Astrocyte Gene TTYH1 as a Hidden Tumor Suppressor
An integrated single-cell and spatial multi-omics study of glioma identifies the astrocyte-associated gene TTYH1 as a tumor suppressor that impedes ...
Tag: Single-Cell RNA Sequencing
Glial Cells Turn Against Gut Neurons in Hirschsprung Disease, Study Finds
A new study shows that the redox enzyme TXNRD1 drives enteric glial cells into a pathological SPP1-high state that suppresses ...
Single-Cell Atlas Reveals How Goat Embryos Turn Intersex, Offering Clues to Human Sex Development
Single-cell RNA sequencing of dairy goat embryos has revealed how stromal and epithelial cells steer gonad development and which genes, ...
Rapamycin Reprograms the Aging Immune System to Cool Inflamed Arteries in Mice
Rapamycin treatment reprogrammed the aging immune system in atherosclerotic mice, reducing plaque macrophages and neutrophils, expanding regulatory T cells, and ...
Macrophage Gene Signatures Predict Colorectal Cancer Prognosis, Machine Learning Study Finds
By integrating bulk and single-cell RNA sequencing with machine learning, researchers in China have identified a nine-gene macrophage signature that ...
Mitochondrial Gatekeeping Genes Offer New Way to Predict Lung Cancer Survival
A machine-learning model built on seven genes tied to mitochondrial outer membrane permeabilization stratifies lung adenocarcinoma patients into distinct survival ...
Machine Learning Pinpoints Two Genes Behind Radiotherapy Resistance in Esophageal Cancer
By integrating single-cell and bulk RNA sequencing with machine learning and laboratory validation, researchers have identified MAP1LC3B and HSD17B10 as ...
Machine Learning Pinpoints Ten-Gene Signature Behind Diabetic Wounds That Refuse to Heal
An integrative study combining transcriptomics, machine learning, single-cell sequencing and mouse validation has identified a ten-gene biomarker panel linked to ...
Single-cell RNA sequencing reveals hidden cell types shaping mosquito disease transmission
A new review details how single-cell RNA sequencing is exposing previously unknown mosquito cell types, blood-meal physiology and pathogen tropisms ...
Machine Learning and Proteomics Reveal Why Kidney Injury Turns Chronic
A multi-omics study of over 53,000 UK Biobank participants identifies 25 proteins, including galectin-3, that predict and may drive the ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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