Stroke Prevention in Sickle Cell Disease Still Rests on Decades-Old Trials
A systematic review of 58 studies finds that transfusion-based stroke prevention established by the STOP trials remains the cornerstone for ...
Tag: Sickle Cell Disease
Study Links Sickle Cell Caregiving to Higher Anxiety
A case-control study in Saudi Arabia finds that caregivers of children with Sickle Cell Disease report significantly higher rates of ...
Review maps CRISPR-Cas9 advances in editing precision, delivery and therapeutic applications
A 2026 review summarizes advances in CRISPR-Cas9 precision, delivery and primary-cell engineering for genetic diseases and diabetes, while the available ...
Sickle Cell Patients Show Activated Platelets and Caspase-1 Activity
A Guadeloupe study found increased platelet activation and caspase-1 activity in adults with sickle cell disease at steady state, with ...
Donald Kohn’s Gene Therapy Breakthroughs Earn Medical Academy Honor
UCLA physician-scientist Donald Kohn’s election to the National Academy of Medicine honors decades of work advancing blood stem cell gene ...
How Molecular Pathology Rewrote the Story of Inherited Blood Disorders
A sweeping narrative review charts how molecular genetics turned non-malignant blood disorders into the proving ground for modern diagnostics and ...
Mitapivat Supercharges ATP Export in Healthy Red Blood Cells but Leaves Sickle Cells Unmoved
A new ex vivo study shows the pyruvate kinase activator mitapivat raises intracellular and exported ATP in healthy red blood ...
Sickle Cell Disease Survival Gains Reveal an Overlooked Midlife Crisis: Early Menopause
A new perspective argues that as women with sickle cell disease survive into midlife, earlier menopause and its overlapping symptoms ...
James LaBelle appointed to lead pediatric cancer and blood diseases programs at Chicagoland Children’s Health Alliance and UChicago Medicine
James LaBelle, MD, PhD, has been formally appointed Service Line Chief of Pediatric Cancer and Blood Diseases for the Chicagoland ...
Proteomic Map of Sickle Cell Retinopathy Reveals Early Photoreceptor Breakdown in Humanized Mice
The first comprehensive proteomic analysis of retinas from humanized sickle cell anemia mice reveals early downregulation of phototransduction and mitochondrial ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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