Tag: senolytics

A new BMC Medicine review explains how chemoradiotherapy can push cervical cancer fibroblasts into a senescent state whose inflammatory secretions ...

A new study in Aging Cell shows that NAD+ metabolic collapse drives senescent CD8+ T cells to fuel ulcerative colitis ...

A new review argues that immune aging and manufacturing stress, not just tumor biology, explain why gamma-delta T cell cancer ...

A new review in Cancer Reports details how the senescence-associated secretory phenotype can both suppress and fuel tumors, and how ...

A comprehensive new review details how senescent fibroblasts, macrophages, keratinocytes and stem cells drive skin aging through ROS, DNA damage, ...

Researchers have identified the little-studied transmembrane protein PTCHD4 as a novel regulator of cellular senescence whose deletion extends lifespan and ...

A new review in Biogerontology argues that senescent cells and their inflammatory secretions act as a convergent, independently targetable driver ...

Researchers have introduced RamanOmics, a label-free strategy combining Raman imaging with spatial and single-cell transcriptomics to map a lipid-linked vibrational ...

A new RamanOmics platform combines Raman chemical imaging with spatial transcriptomics to reveal the biochemical remodeling that defines senescent cells.

A new review argues that neurons can acquire senescence-like states in aging and neurodegenerative disease, but peripheral senescence markers cannot ...