Effects of zoledronic acid on senescence and SASP markers
“In the present study, we used multiple complementary approaches to evaluate the possible effects of zoledronic acid on cellular senescence.” ...
Tag: senescence
A chronic wound model to investigate skin cellular senescence
“Here, we report a chronic wound healing model that can be used to decipher the paradoxical role of cellular senescence ...
Metformin & leucine prevent cellular senescence & proteostasis disruption
“Cellular senescence and disrupted proteostasis induced by myotube atrophy are prevented with low-dose metformin and leucine cocktail.” Credit: 2023 Petrocelli ...
Senescence and extracellular vesicles: novel partners in vascular amyloidosis
“ there has been limited research to date on the effect of cellular ‘ageing’, termed senescence, on amyloidosis.” Credit: 2023 ...
Aging | Cellular senescence: when growth stimulation meets cell cycle arrest
“Growth and aging are driven by overlapping signaling pathways.” Credit: 2023 Blagosklonny “Growth and aging are driven by overlapping signaling ...
Cellular senescence plays a significant role in cerebral tumors
Glioblastoma, the most common adult brain cancer, affects 2 to 5 in 100,000 individuals. While the incidence of the disease ...
Aging | Single nuclei profiling identifies cell specific markers of skeletal muscle aging, frailty, and senescence
“Our study provides several insights into human skeletal muscle aging.” Credit: 2022 Perez et al. “Our study provides several insights ...
Early green, early brown – climate change leads to earlier senescence in alpine plants
Global warming is leading to longer growing seasons worldwide, with many plants growing earlier in spring and continuing longer in ...
Aging | IGF1 gene therapy in middle-aged female rats delays reproductive senescence through its effects on hypothalamic GnRH and kisspeptin neurons
“Based on our findings, we propose IGF1 gene therapy to delay reproductive senescence as a potential strategy to optimize lifespan ...
Buck Institute awarded $14 million from NIH to study cellular senescence and Alzheimer’s
Buck Institute professors Judith Campisi, PhD and Lisa Ellerby PhD, have been awarded a $14.3 million grant from the NIH’s ...
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UTHSC researchers’ work on human pangenome aids understanding of common chromosomal abnormality
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Weather anomalies are keeping insects active longer
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Mount Sinai researchers use new deep learning approach to enable analysis of electrocardiograms as language
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Healthy vascular fat during menopause may stave off dementia later in life
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Renowned sociologist and Black Voices Quintet set to dazzle at HDR UK’s Black Internship Programme Opening Ceremony 2023
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Null results research now published by major behavioral medicine journal