Scaffold Protein LAMB1 Drives Esophageal Cancer Growth Through JAK2/STAT3 Pathway
New research shows that the extracellular matrix protein LAMB1 accelerates esophageal squamous cell carcinoma by activating JAK2/STAT3 signaling, suggesting it ...
Tag: ruxolitinib
Ruxolitinib Rescue Saves Child From Severe Liver GVHD After Thalassemia Transplant
A pediatric case report details the successful treatment of severe liver-predominant acute graft-versus-host disease after stem cell transplantation for beta-thalassemia ...
Skin Rash Vanishes When Cancer Drug Targets Inflammation in Rare Syndrome Case
A Swiss case report shows that the JAK1/2 inhibitor ruxolitinib completely resolved steroid-refractory histiocytoid Sweet syndrome in a polycythemia vera ...
Ruxolitinib Shows Stronger Response in Primary Than Secondary HLH, Meta-Analysis Finds
A systematic review of 542 patients finds ruxolitinib-based regimens achieve an 87.2 percent overall response rate in hemophagocytic lymphohistiocytosis, with ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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