Nanopore Method Maps Active tRNAs During Cellular Stress
A new nanopore sequencing method called tRIBO-seq distinguishes between ribosome-associated and total tRNAs, revealing distinct dynamics under stress.
Tag: ribosome profiling
Weaning stress shifts codon use and gut microbes in piglet immune cells
A study in weaned piglets links weaning stress to a coordinated shift toward GC-rich codon usage in host immune genes ...
Unstressed yeast study links Zuo1 surveillance to predicted protein disorder
A study in unstressed yeast found that loss of the ribosome-associated chaperone Zuo1 allowed transcripts encoding more disordered proteins to ...
How the cell builds its membrane proteins: new view of the EMC-bound translocon
Combining ribosome profiling, cryo-electron tomography and photocrosslinking, researchers have revealed how the ER membrane protein complex is recruited to the ...
Ribosomes Are Not All Alike: Review Maps the Rise of Specialized Protein Factories
A new review argues that ribosomes vary in composition and chemical state across biological contexts and proposes a four-step framework ...
Tiny but mighty: microproteins emerge as regulators of disease and future precision therapeutics
A new review in 3 Biotech charts how tiny proteins encoded by small open reading frames regulate cancer, heart disease, ...
Hidden Microproteins in the Aging Brain Could Reshape Alzheimer’s Research
An atlas of the aged human brain catalogs over 1,000 high-confidence microproteins, including an MKKS-encoded microprotein reduced in Alzheimer's disease ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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