Chemotherapy drug taxol reshapes microtubules to switch on a key cell signal
New research shows that taxane chemotherapy drugs expand the microtubule lattice and thereby release the signalling protein GEF-H1, rapidly activating ...
Tag: RhoA
Blood Fats May Fuel Lung Cancer Spread Through a Hidden Metabolic Switch
New research reveals that elevated triglycerides drive lung cancer metastasis through a lipid beta-oxidation and RhoA-dependent cytoskeletal pathway that tumour ...
Blood Vessel Protein Epac1 Found to Fuel Melanoma Growth Through YAP/TAZ Signalling
New research shows that the endothelial protein Epac1 drives melanoma growth and angiogenesis by coordinating VEGFR2 signalling, RhoA-dependent cytoskeletal dynamics, ...
Thyroid Cancer Protein Rewires Tumor Metabolism and Drives Drug Resistance
New research shows the protein ECT2 drives papillary thyroid carcinoma growth by suppressing lipoic acid metabolism, activating PI3K/AKT signaling and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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