Macrophage Metabolic Switch Could Heal Diabetic Wounds
A macrophage enzyme called transketolase emerges as a metabolic checkpoint controlling blood vessel regeneration in diabetic wounds, and a nanozyme ...
Tag: reprogramming
Bacterial teamwork and a single metabolite drive the fierce heat of Daqu fermentation
Deep in the wheat blocks of high-temperature Daqu, the fermentation starter that anchors the production of premium Moutai-flavor Baijiu, temperatures ...
Sugar tags on proteins reveal how microalgae survive CO2 starvation
A dual proteomics and glycoproteomics study of Nannochloropsis oceanica maps 5,136 proteins and 459 N-glycosylation sites, showing that sugar modifications ...
Induced Pluripotent Stem Cells Take Aim at Cancer Prevention, Therapy, and Tumor Modeling
A new review highlights how induced pluripotent stem cells are being engineered into immune cells, cancer vaccines, and tumor models ...
Memory T Cell Metabolism May Decide Who Keeps Tuberculosis at Bay
A multi-platform study links fatty acid oxidation in stem-like memory CD4+ T cells to durable tuberculosis control, while glycolytic effector ...
Rewiring the Tumor Engine: How Metabolism Could Become Cancer’s Next Weak Spot
New research highlights microRNAs, mitochondrial ribosomal proteins and lactate signaling as promising targets against cancer's metabolic reprogramming.
Common Sunscreen Chemical Benzophenone-1 Reprograms Immune Cells to Fuel Breast Cancer Growth in Lab Study
New research shows the UV filter benzophenone-1 shifts macrophages toward a tumor-supportive M2-like state, and the conditioned medium from these ...
RNA edit swaps out OCT4 to make better stem cells
Researchers discovered that the RNA-modifying enzyme PUS7 pseudouridylates the noncoding RNA 7SK to recruit the BAF chromatin-remodeling complex, enabling a ...
A Molecular License to Change: How One Gene Unlocks Natural Cell Identity Switching
New research in C. elegans reveals that the gene lin-15A enables natural cell identity conversion by weakening chromatin-based safeguards rather ...
Long-Read Genome Sequencing Powers a New, Deeply Characterized iPSC Resource for Lab Modeling
Researchers at the Coriell Institute have created a publicly available iPSC resource with HiFi long-read whole-genome sequencing, pharmacogenomic and HLA ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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