Tag: Rapamycin

Researchers argue that the popular slogan of extending healthspan but not lifespan is scientifically incoherent and ethically untenable as a ...

New research reveals that the cellular recycling protein p97/VCP directly regulates the autophagic degradation of androgen-binding protein in Sertoli cells, ...

A cross-species study in Nature Aging shows that lipid acyl chains lengthen consistently with age across mice, worms, flies and ...

A controlled study of 80 Beagles maps non-linear, sex-stratified immune aging across the canine lifespan and finds exploratory evidence that ...

Rapamycin treatment reprogrammed the aging immune system in atherosclerotic mice, reducing plaque macrophages and neutrophils, expanding regulatory T cells, and ...

Rapamycin-loaded nanoliposomes inhibited mTORC1-driven senescence in rat disc cells and slowed intervertebral disc degeneration in vivo, pointing toward an injectable ...

A protein once viewed as a mere nutrient store in fruit flies turns out to amplify mTORC1 signaling, control ribosomal ...

A comprehensive new review details how senescent fibroblasts, macrophages, keratinocytes and stem cells drive skin aging through ROS, DNA damage, ...

A new study built 49 transcriptomic aging clocks across human tissues and mapped how thousands of drugs show structured but ...

Menopause, that long-overlooked life transition once brushed aside as a foregone conclusion of aging, has quietly become a focal point ...