Jonathan the 194-Year-Old Tortoise Reveals a Genetic Secret to Aging Slowly
A Vanderbilt-led team sequencing the genome and epigenome of Jonathan, a 194-year-old giant tortoise on St. Helena, found that promoters ...
Tag: Rapamycin
Zebrafish Reveal a Surprising Trick for Rebuilding Nerves: Letting Dendrites Go First
New research in adult zebrafish shows that transient dendritic pruning driven by repressed mTORC1 signaling is essential for efficient axonal ...
Why Extending Healthspan Without Lifespan Is a Misguided Goal for Aging Science
Researchers argue that the popular slogan of extending healthspan but not lifespan is scientifically incoherent and ethically untenable as a ...
Cellular Recycling Machine Linked to Male Fertility Hormone Control
New research reveals that the cellular recycling protein p97/VCP directly regulates the autophagic degradation of androgen-binding protein in Sertoli cells, ...
Aging Makes Fatty Chains Longer, and Shortening Them Extends Lifespan
A cross-species study in Nature Aging shows that lipid acyl chains lengthen consistently with age across mice, worms, flies and ...
Dogs Reveal Sex-Specific Immune Aging Patterns and Early Clues on Anti-Aging Drugs
A controlled study of 80 Beagles maps non-linear, sex-stratified immune aging across the canine lifespan and finds exploratory evidence that ...
Rapamycin Reprograms the Aging Immune System to Cool Inflamed Arteries in Mice
Rapamycin treatment reprogrammed the aging immune system in atherosclerotic mice, reducing plaque macrophages and neutrophils, expanding regulatory T cells, and ...
Rapamycin Nanoparticles Rejuvenate Aging Spine Discs by Silencing a Cellular Aging Switch
Rapamycin-loaded nanoliposomes inhibited mTORC1-driven senescence in rat disc cells and slowed intervertebral disc degeneration in vivo, pointing toward an injectable ...
Fruit fly storage protein found to be a master switch of aging
A protein once viewed as a mere nutrient store in fruit flies turns out to amplify mTORC1 signaling, control ribosomal ...
Scientists Map the Cellular Drivers of Skin Aging and the Race to Reverse Them
A comprehensive new review details how senescent fibroblasts, macrophages, keratinocytes and stem cells drive skin aging through ROS, DNA damage, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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