Heart’s Resident Cells, Not Immune Cells, Drive Damage After Heart Attacks
A bone marrow chimera study in mice shows that deleting the CLEC4E receptor in cardiac resident cells, rather than in ...
Tag: Proteomics
Engineered vesicles deliver miR-204 to triple-negative breast cancer cells in preclinical tests
Researchers engineered GE11-targeted vesicles that delivered tumor-suppressive miR-204 into EGFR1-positive triple-negative breast cancer cells, inhibiting their growth in lab and ...
Processed diets tied to gestational diabetes and altered blood proteins in Miao women
A matched case-control study of 78 Miao pregnant women in Guizhou, China, linked a processed dietary pattern to higher odds ...
Cancer cells on the move shed giant vesicles packed with whole genomes
Migrating cancer cells shed large vesicles called MoVes that carry whole genomic DNA, organelles and EMT-linked proteins, according to a ...
New Mouse Model Reveals How RMND1 Mutations Disrupt Mitochondrial Energy Production
The first knock-in mouse carrying the recurrent human RMND1 p.(Asn238Ser) mutation recapitulates severe multisystem mitochondrial disease, revealing widespread OXPHOS defects ...
Witnessing Defeat Is Not the Same as Suffering It: Mouse Study Shows Two Stress Models Diverge
A controlled mouse study finds that witnessed social defeat produces overlapping but distinct behavioral and hippocampal molecular effects from direct ...
Parasite Larvae and Their Vesicles Push Gut Cells in Opposite Directions in Lab Study
In laboratory experiments, live Strongyloides stercoralis larvae triggered pro-inflammatory responses in human intestinal epithelial cells while the parasites' extracellular vesicles ...
E3 Ligase UBE4B Tags VPS35 for Destruction, Steering Cancer Cell Behavior in Context-Dependent Ways
A new study shows the E3 ligase UBE4B ubiquitinates and degrades VPS35, with opposing effects on cancer cell proliferation and ...
CSF Protein Signals Stay Stable Through Repeated Freeze-Thaw Cycles in High-Throughput Assay Test
A new evaluation of the Olink Explore 3072 proximity extension assay in cerebrospinal fluid finds that protein detectability and variability ...
Transcriptomics Reveals How Insects Cope With Heat, Pesticides and Pathogens
A systematic review of 166 studies shows how transcriptomics is decoding insect development, stress responses and pest management at the ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!