Simulations reveal how yeast topoisomerase I may grip the transcription machinery
Computational modeling and 200-nanosecond simulations reveal a plausible, stable interaction interface between yeast topoisomerase I and the RNA polymerase III ...
Tag: protein-protein interaction
Massive Molecular Screen Targets a Fatal Weak Point in Tuberculosis Transcription Machinery
Researchers screened more than 87,000 compounds against the essential interaction between the tuberculosis bacterium's RNA polymerase and the transcription factor ...
New AI Model Reads Protein Clues Three Ways to Map the Cell’s Contact Network
A new multimodal AI framework called TriCCA-PPI fuses sequence, structure, and functional data through chained cross-attention to predict protein-protein interactions ...
Metarrestin’s Anti-Cancer Mechanism Mapped Through Network Pharmacology
A new network pharmacology study maps how the anti-metastatic drug metarrestin rewires cancer cell protein networks and identifies the cell-cycle ...
AI-guided screen finds drug-candidate molecules that shield cells from oxygen starvation
A deep-learning-guided virtual screen identified four molecules that block the HIF-1α/VHL interaction, including the approved myeloma drug ixazomib, which protected ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!