Tag: Protein Engineering

A new parallel deep learning framework combining CNN and Transformer branches with thermodynamic regularization improves the prediction of mutation-induced protein ...

Researchers used a protein language model and an epistatic rescue algorithm to computationally humanize a bacterial peptide transporter, paving the ...

Researchers have engineered an enzyme variant that depolymerizes post-consumer PET in natural seawater at 37 degrees Celsius, achieving monomer yields ...

A new Microbial Biotechnology editorial shows how engineered microbes and enzymes are being deployed against fungal disease, diabetes, plastic waste ...

Researchers have engineered S1.0, a ribosome-display synthetic nanobody library that yields high-affinity binders compatible with the Legobody cryo-EM toolkit without ...

Researchers have designed new protein subunits that integrate with a natural nanopore to create semisynthetic conduction pores with confirmed lumen ...

Researchers in Taiwan have engineered E. coli transaminases to biosynthesize chain-elongated unnatural amino acids one carbon at a time, reaching ...

A Cell Research article examines how artificial intelligence-guided engineering of gasdermin pore-forming proteins could be harnessed to selectively eliminate virus-infected ...

Researchers have engineered proteins that remain inactive until nitric oxide in inflamed tissue chemically restores their function, enabling targeted therapeutics, ...

A new study in Nature Biomedical Engineering combines AI-designed protein binders with CAR engineering to define the sequence and structural ...