Tag: progression

Preclinical tissue, cell, and xenograft experiments found that MG53 promoted AMPKα degradation, reduced glycolytic metabolism and tumor growth, and increased ...

For tens of thousands of women living with metastatic breast cancer, the arrival of cyclin-dependent kinase 4/6 inhibitors transformed a ...

Deep inside hiring rooms, promotion committees, and project meetings across Ghana's water, sanitation, and hygiene sector, a quiet cognitive machinery ...

Benzoylaconine, a detoxified metabolite of aconitine, arrests colorectal cancer cells at the G1/S transition by directly binding CDK2 and MMP2, ...

Scientists have uncovered a previously hidden layer of the genome that appears to help KRAS-mutant colorectal cancer grow and spread. ...

For patients with EGFR-mutant lung adenocarcinoma whose cancer has already spread to the brain, third-generation EGFR-TKI drugs such as osimertinib ...

CDCA5, better known as Sororin, shields hepatocellular carcinoma cells from iron-driven cell death by boosting PP2Ac, dampening p53 signaling, and ...

A sweeping new review maps the two-way molecular conversation between the oral microbiome and the immune system in periodontitis, revealing ...

Prognostic models sit at the heart of modern clinical decision-making. They take measurable patient characteristics—age, biomarkers, tumor grade, comorbidities—and convert ...

A long non-coding RNA called RBMS3-AS3 has emerged as a powerful molecular accomplice in ovarian cancer, according to a new ...