Tag: preclinical research

A five-aptamer panel reduced tumor-cell viability, proliferation, migration and colony formation in several triple-negative breast cancer cell lines, with variable ...

A patient-derived colon cancer liver-metastasis cell line, CRC-X1, was stably passaged through 59 generations, formed tumors in 60% of mouse ...

A Schistosoma japonicum-derived microRNA reduced liver fibrosis in carbon-tetrachloride-treated mice alongside lower stellate-cell activation, collagen deposition and inflammatory signaling.

Cell-culture and mouse experiments found that low-concentration simvastatin promoted osteogenic activity and endothelial network formation through a process associated with ...

A 2026 editorial synthesizes epidemiological, clinical and preclinical evidence highlighting candidate pharmacological targets for alcohol use disorder while emphasizing that ...

A preclinical Singapore study identified PAI-1 and S100A10 as ascites-associated drivers of peritoneal metastases and found that the PAI-1-targeting nanobody ...

A mini review finds that preclinical evidence links repeated or prolonged sevoflurane exposure during development with neuroinflammation, microglial activation and ...

A 2026 review finds that several natural compounds alter PPARγ-related pathways in cellular and mouse models of ulcerative colitis, but ...

A preclinical study found that fucoidan-coated zein nanoparticles increased psoralen uptake in 4T1 breast-cancer cells, prolonged tumor-associated retention in mice, ...

A systematic review of 14 in vitro studies found that natural products showed antiproliferative and proapoptotic activity in human mucoepidermoid ...