A comprehensive review of 309 studies reveals that chromatin remodeling complexes drive the progression and phenotypic heterogeneity of major cardiomyopathies, ...
A new review proposes that the histone marks H3K4me3 and H3K27me3 may keep cold-responsive genes in cotton poised for rapid ...
Deleting the Polycomb protein PCGF1 in the mouse dorsal forebrain selectively blocks astrocyte production by lifting repression of N4bp1, a ...
A new study finds that the Drosophila protein Rumpelstiltskin maintains the Homie insulator barrier and shapes Polycomb domain interactions in ...
A new study maps about 1,100 sites where PRC2 rapidly re-establishes itself in mouse embryonic stem cells after reversible depletion ...
Researchers in Barcelona report that a six-gene activity score, anchored by the Polycomb factor PHF19, divides acute myeloid leukaemia patients ...
A Nature Genetics study shows that the histone mark H2Aub laid down by PRC1 guides the reestablishment of Polycomb repression, ...
A comprehensive epigenomic map of medulloblastoma reveals that the chromatin regulator KDM2B sustains the highest-risk tumor subgroups by locking neuronal ...
New research reveals that maternal seed coat tissues in plants use H3K27me3 histone demethylation to control auxin delivery and thereby ...
Ciapponi and colleagues have determined the cryo-EM structure of the canonical PRC1 holocomplex, revealing how its architecture coordinates assembly, H2A ...
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