Tiny RNA Molecule May Explain Why Some People Resist Tuberculosis Infection
A new PLOS Pathogens study finds that the microRNA-1246 regulates macrophage lipid metabolism and helps explain why some household contacts ...
Tag: PLOS Pathogens
Light, Hunger, and Humidity: The Genetic Switches That Launch a Deadly Crop Pathogen’s Spores
New research reveals how nitrogen starvation, a cryptochrome photoreceptor, and humidity checkpoints govern the transcriptional program that drives spore formation ...
Parasitic Worm’s Molecular Switch Reveals How It Adapts to Its Rat Host
Researchers have identified the nuclear receptor AcNR1F as a ligand-activated molecular switch that regulates cuticle remodeling, development, and reproduction in ...
Deadly Toxin Rewires Tuberculosis Bacterium to Survive Tryptophan Starvation
A tuberculosis toxin that destroys only the tryptophan transfer RNA tricks the bacterium into boosting amino acid synthesis while preserving ...
Immune Protein GBP7 Turns Traitor, Helping Herpes Simplex Virus Translate Its Way to Infection
A new PLOS Pathogens study shows that the interferon-induced GTPase GBP7 unexpectedly promotes HSV-1 infection by activating the translation factor ...
Hepatitis C Vaccine Design Gains Ground as Structures Reveal How Naive Antibodies See Viral Envelope
New structural and biochemical analyses of the hepatitis C virus E2 glycoprotein show that germline-reverted broadly neutralizing antibodies recognize the ...
Zika Virus Splits One Protein Into Two Forms With Opposing Jobs in Its Life Cycle
New research in PLOS Pathogens shows that Zika virus produces two isoforms of the NS2A protein, with the full-length form ...
Vaccination May Speed Up Influenza Evolution, Model Warns
A coupled epidemiological and evolutionary model of influenza shows that vaccination can accelerate viral escape and even raise infection incidence ...
Bacterial Biofilms May Trigger the Autoantibodies Behind Lupus Kidney Damage
New research in mice shows that curli amyloid fibers from Salmonella and E. coli biofilms can drive the production of ...
How a Plant-Killing Fungus Turns Deadly in Humans
A new PLOS Pathogens review explains how accessory chromosomes, iron and sterol metabolism, and immune-evasion traits allow Fusarium oxysporum, a ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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