Immune Complexes of SARS-CoV-2 RNA and Nucleocapsid Drive Inflammation
A PLOS Pathogens study shows that SARS-CoV-2 RNA, nucleocapsid protein and anti-N IgG1 form immune complexes that trigger inflammatory cytokines ...
Tag: PLOS Pathogens
HIV-1 Spread Between Macrophages Sidesteps the BST-2 Tetherin Restriction Factor
HIV-1 cell-to-cell infection of macrophages escapes the BST-2 tetherin restriction factor independently of Vpu, while remaining sensitive to the protease ...
Defective Viral Genomes of PRRSV-2 Show Antiviral Activity Against Multiple Strains
A PLOS Pathogens study provides the first systematic characterization of defective viral genomes generated during PRRSV-2 infection, linking them to ...
Oral uracil raises rectal SIV susceptibility in macaques
Oral uracil treatment increased susceptibility to rectal SIV acquisition in macaques despite limited measurable intestinal immune changes, while uracil suppositories ...
Scientists Launch Global Push to Outmaneuver a Fungus That Kills More Than Half Its Victims
A new PLOS Pathogens review introduces the NIAID-funded MUCOR-ADVANCE consortium, which unites diagnostics, immunotherapy and pathogenesis research against mucormycosis, a ...
MARK3 kinase drives antiviral defense through GEF-H1 and TBK1 signaling
A new study identifies MARK3 as a kinase that promotes type I interferon production by phosphorylating GEF-H1 and activating the ...
Cryptococcal Meningitis Reshapes HIV-1 Populations in the Brain
A study of people with HIV-1 and cryptococcal meningitis reveals diverse mechanisms shaping viral populations in the central nervous system, ...
Cytomegalovirus Hijacks Host Chromatin Remodeler MORC2 to Fuel Viral Genome Repair
A new PLOS Pathogens study shows that human cytomegalovirus induces and recruits the host chromatin remodeler MORC2 to viral replication ...
Intranasal Herpes Virus Remodels Brain Immune Cells in a Region-Specific Pattern
A multiomic study in PLOS Pathogens shows that intranasal HSV-1 infection drives localized, interferon-dominated remodeling of microglia in discrete brainstem ...
Cell-Penetrating Receptor Mimic Delivers a Long-Sought Blow Against Enteroviruses
Researchers engineered a cell-penetrating peptide that mimics the intracellular function of the SCARB2 receptor, broadly inhibiting EV-A71 and CV-A16 in ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!