Hidden Genetic Threads Link Cancers Through Shared Regions and Pathways
A new PLOS Genetics study shows that shared genetic susceptibility across cancers is modest genome-wide but becomes structured and biologically ...
Tag: PLOS Genetics
Where a Gene Sits on the Bacterial Chromosome May Shape Its Expression Through Selection
A new PLOS Genetics study finds that bacterial gene positions along the chromosome show gradients in mean and growth-dependent expression ...
DNA Repair Enzymes RecA and UvrD Emerge as Central Players in Antibiotic Persister Survival
New genetic analysis in Escherichia coli reveals that the DNA repair hub proteins RecA and UvrD are essential for fluoroquinolone ...
Rat Study Reveals the Womb May Shield Babies With Classic Galactosemia Before Birth
A GALT-null rat model shows that fetal growth in classic galactosemia is impaired only when the mother and all siblings ...
Chemical Tag on mRNA Reveals Hidden Switch That Controls Hair Growth Cycles
A new PLOS Genetics study shows that the RNA modification enzyme METTL1 controls hair follicle cycling by stabilizing HOXC13 messenger ...
New Sparse Regression Method Tames Biobank-Scale Genetic Data for Risk Prediction
Researchers have adapted a two-stage sparse regression method called uniLasso to the UK Biobank, producing polygenic risk scores that match ...
Fly Study Reveals How the RNA Modifier Mettl16 Shapes Development and Fertility
New research in fruit flies shows that the RNA methyltransferase Mettl16 is dispensable for survival but essential for fertility, acting ...
A Molecular License to Change: How One Gene Unlocks Natural Cell Identity Switching
New research in C. elegans reveals that the gene lin-15A enables natural cell identity conversion by weakening chromatin-based safeguards rather ...
Zebrafish Rewire Their Guts Over Generations to Survive Protein Starvation
A new study shows that zebrafish lacking a key protein-absorption gene gradually recover over generations through genome-wide transcriptional changes that ...
Misfolded Proteins May Explain a Hidden Share of Inherited Deafness
A large-scale computational study finds that protein misfolding may underlie a substantial share of hereditary hearing loss, reclassifying tens of ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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