Gut Bile Acid Rejuvenates Aging Bone Stem Cells to Fight Postmenopausal Osteoporosis
A gut bacteria-derived bile acid called hyodeoxycholic acid restores aging bone marrow stem cells and reverses bone loss in a ...
Tag: PINK1
Massive Epigenetic Study Reveals Why Parkinson’s Disease Strikes Men and Women Differently
A two-stage epigenome-wide meta-analysis of more than 2,000 individuals has identified thousands of DNA methylation sites where Parkinson's disease affects ...
How Pathogens Hijack Mitophagy and What It Means for Treating Infection
A new review details how bacteria and viruses hijack or block the mitochondrial quality-control pathway of mitophagy to survive, evade ...
Scientists Reveal How the PARK7–PINK1 Protein Axis Controls Stem Cell Reprogramming
A new study shows that the PARK7–PINK1 protein axis, known for its links to Parkinson's disease, regulates stem cell reprogramming ...
How Failing Cellular Housekeeping Fuels Brain Disease Through a Viral Alarm System
A new review in the Journal of Translational Medicine details how impaired mitophagy allows mitochondrial DNA to trigger cGAS–STING-driven neuroinflammation ...
Kisspeptin-10 Shows Promise Against Obesity-Driven Testicular Damage in Rat Study
A new rat study shows the puberty-regulating hormone Kisspeptin-10 reduces testicular oxidative stress, improves sperm quality, and boosts mitophagy-related proteins ...
Cellular Recycling Switch SIRT1-FOXO1 May Hold Key to Taming Brain Inflammation
New research shows that the SIRT1-FOXO1 signaling axis acts as a molecular brake on excessive mitophagy and glycolytic metabolism in ...
Calcium-Rich Bone Environment Helps Osteosarcoma Cells Survive Chemotherapy
Researchers have discovered that the calcium-rich bone microenvironment drives chemotherapy tolerance in osteosarcoma through an ORAI3–Ca²⁺–NFAT4–PINK1 mitophagy axis that can ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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