Rutin shields cerebellar neurons from acrylamide damage by activating PI3K/AKT signaling in rats
A natural plant compound found in everyday foods such as buckwheat, apples and onions may offer protection against one of ...
Tag: PI3K-AKT signaling
Lion’s Mane Mushroom Glycoprotein Eases Diabetes in Mice, Study Finds
A glycoprotein isolated from lion's mane mushroom reduced blood glucose, improved insulin sensitivity, and reshaped gut microbiota in diabetic mice.
Gut Microbe and Its Fatty Acid Break the Inflammatory Loop That Drives Obesity
A cross-species study shows that the gut bacterium Clostridium butyricum and its metabolite butyrate alleviate obesity by disrupting an LPS-EGR1 ...
Collagen Clue: How COL6A1 May Drive Bile Duct Cancer’s Deadly Spread
A new review in Cancer Reports proposes that the extracellular matrix protein COL6A1, overexpressed in the fibrotic stroma of cholangiocarcinoma, ...
Bile Acid Sensor FXR Drives Liver Regeneration by Rebuilding Its Immune Cell Army
New research shows that the bile acid receptor FXR coordinates monocyte recruitment and Kupffer cell proliferation through CCR2 and CSF1/PI3K/Akt ...
Scientists Uncover Molecular Switch That Helps Prostate Cancer Spread to Bone
A new study reveals that an AURKA-driven phosphorylation and SUMOylation cascade stabilizes the protein SPICE1, fueling prostate cancer's spread to ...
Hidden RNA Switch Drives Deadly Scarring of the Lungs, Study Finds
Researchers have identified an RNA-based molecular circuit involving H19, miR-103a-3p and TRIOBP that drives the scar-forming transformation of lung cells ...
Gut Microbe Veillonella Emerges as a Potential Driver of Pancreatic Cancer Progression
A new integrated study finds the gut bacterium Veillonella enriched in advanced pancreatic cancer patients and provides functional and genetic ...
CD39 Emerges as a Deadly Biomarker and Drug Target in Bile Duct Cancer
New research shows that the immune enzyme CD39 is overexpressed in cholangiocarcinoma, drives tumor growth and metastasis through the ANXA2 ...
Oregano Essential Oil Boosts Immunity and Fights Oxidative Stress in Beef Cattle, Multi-Omics Study Shows
An integrated transcriptomic and metabolomic study of Pingliang red cattle finds that dietary oregano essential oil raises antibody and antioxidant ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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