Gut Microbes Shield Fly Larvae From Antimicrobial Triclosan’s Immune Damage
A new Drosophila study shows that gut bacteria blunt triclosan's damage to larval immune cells, and that germ-free larvae suffer ...
Tag: phagocytosis
Immune Receptor LAIR1 Blocks Cancer Cell Engulfment in Brain Tumours
New research in the British Journal of Cancer shows that the collagen-binding receptor LAIR1 disables the phagocytic machinery of glioma-associated ...
Blocking EP300 Rewires Scar-Associated Macrophages to Fight Acute Liver Failure
A new Nature Communications study shows that inhibiting the epigenetic enzyme EP300 restores the antibacterial function of scar-associated macrophages by ...
Microplastics Overwhelm Liver Immune Cells and Derail Metabolism in Mice
A twelve-week mouse study shows that microplastics and nanoplastics accumulate in liver macrophages and disrupt metabolism in strikingly different ways ...
Engineered Macrophages Emerge as a New Frontier in Cell Therapy for Solid Tumors
A new review details how chimeric antigen receptor-engineered macrophages are overcoming the barriers that stalled CAR-T therapy in solid tumors, ...
Lipid Nanoparticle CAR Engineering Reveals Synergy Between T Cells and Macrophages Against Leukemia
A new study shows that lipid nanoparticle-delivered CAR mRNA engineers both human T cells and macrophages against CD19-positive leukemia cells, ...
Snake Virus Study Reveals Hidden Immune Damage Behind a Deadly Reptile Disease
A comprehensive study of 133 boa constrictors shows that boid inclusion body disease selectively impairs phagocytic immune cells and lowers ...
The Don’t Eat Me Signal: How CD47 Shapes Cell Clearance in Cancer, Heart Disease and the Brain
A new review details how the CD47 don't eat me signal regulates efferocytosis and shapes disease outcomes in cancer, atherosclerosis ...
Sea Cucumber Immune Cells Revealed in Unprecedented Detail by Single-Cell Sequencing
A single-cell RNA sequencing study of the sea cucumber Holothuria forskali has identified ten distinct coelomocyte populations, including a clearly ...
Immune Checkpoint TREM2 Emerges as a Switch to Supercharge CAR Macrophages Against Breast Cancer
New research shows that blocking the TREM2 receptor reprograms HER2-targeted CAR macrophages from suppressive to inflammatory, tumor-engulfing cells in breast ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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