Cancer Cells Rewire Immune Neutrophils Through a Fumarate-Driven Metabolic Switch, Study Finds
A new Nature Cancer study reveals that the kinase GSK3β in colorectal tumor cells drives fumarate accumulation that epigenetically reprograms ...
Tag: PD-L1
How Your Face Ages: Genes, Inflammation and Blood Fats Reveal the Biology of Looking Older
A UK Biobank study of 435,078 people uses causal inference and multi-omics to map sex-specific inflammatory and lipid pathways that ...
PET Scan Glucose Uptake Offers Clues to Immunotherapy Biomarker in Esophageal Cancer
A retrospective study of 89 patients finds that 18F-FDG PET/CT metabolic parameters, particularly SUVmax, are statistically associated with PD-L1 expression ...
Immunotherapy Brings Three-Year Survival in Rare, Usually Fatal Lung Vascular Cancer Syndrome
A Japanese case report describes more than three years of progression-free survival in pulmonary tumour thrombotic microangiopathy after prompt nivolumab ...
Immune Cells Cluster Around Blood Vessels to Predict Lung Cancer Immunotherapy Success
New spatial profiling research shows that the positioning of cytotoxic T cells around tumor blood vessels predicts which non-small cell ...
One Dose of a New Immunotherapy Combo Triggered Four Organ Crises in a Lung Cancer Patient
A single cycle of atezolizumab plus tiragolumab triggered simultaneous myocarditis, hepatitis, thrombocytopenia, and dermatomyositis in a lung cancer patient, whose ...
Immune Therapy Plus Chemotherapy Erases Stage IIIB Lung Tumor Before Surgery
A stage IIIB lung squamous cell carcinoma patient achieved a pathological complete response after neoadjuvant sugemalimab plus chemotherapy, with biomarker ...
Tiny Bubble Messengers Could Transform How Gastric Cancer Is Detected and Treated
A new review maps how extracellular vesicles drive gastric cancer progression and how engineered versions could become diagnostics and drug ...
Meningioma Study Points to CD73 as a Candidate Biomarker of Tumor Grade
An exploratory Brazilian study of 40 surgically resected meningiomas found that CD73 expression rises while PD-L1 falls in WHO grade ...
Hidden Molecular Switch Links H. pylori Infection to Aggressive Gastric Cancer
A new study reveals how the ONECUT2-YOD1-STAT3-PD-L1 signaling axis drives malignant progression and immune evasion in H. pylori-associated gastric cancer.
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!