Chalcone Library Yields Nanomolar MAO-B Inhibitors for Neurodegeneration
Researchers have identified a morpholine-substituted chalcone, TC12, that inhibits monoamine oxidase B at 11 nanomolar with over 3,600-fold selectivity and ...
Tag: Parkinson’s disease
EEG Bursts Reveal Distinct Brain Rhythms Behind Parkinson’s and Freezing of Gait
A multi-site EEG study finds that Parkinson's disease alters the timing of low-beta brain bursts while theta burst amplitude tracks ...
Polyamine Metabolism Emerges as a Central Player in Neurological Disease
A new review links dysregulated polyamine metabolism to Alzheimer's, Parkinson's, ALS, and other neurological disorders, outlining molecular mechanisms and emerging ...
New PET Tracer Candidate Flags Alpha-Synuclein in Lewy Body Disease But Misses MSA
A new tritium-labeled alpha-synuclein PET ligand, ³H-M503-1619, binds pathological aggregates in postmortem tissue from Lewy body diseases but not in ...
SPECT Rivals PET in Head-to-Head Test of Parkinson’s Brain Scans
A head-to-head trial shows modern multi-pinhole SPECT matches PET for dopamine transporter imaging in uncertain parkinsonism, while neuromelanin and iron ...
Managing the mental state may ease anxiety-related freezing of gait in Parkinson’s
A randomized controlled trial in npj Parkinson's Disease tested whether strategies for managing anxiety and the mental state can reduce ...
Sexual and Mental Health Shape Quality of Life in Parkinson’s Disease
A new study applying the revised Wilson and Cleary model finds that mental health and sexual function are as important ...
Sleep Problems May Signal Widespread Functional Decline in Parkinson’s Disease
A new study in npj Parkinson's Disease links sleep disorders to decline across cognitive, motor, and daily-living domains beyond what ...
Tiny Biosensors Could Detect Alzheimer’s and Parkinson’s Years Before Symptoms
A comprehensive review shows that miniaturized biosensor platforms can detect Alzheimer's, Parkinson's, and prion disease biomarkers at extraordinary sensitivity, but ...
Parkinson’s infusion therapy shows manageable psychiatric risks in real-world study
A real-world study of 77 advanced Parkinson's patients finds that neuropsychiatric side effects of foslevodopa/foscarbidopa infusion occur more often than ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!