How Failing Cellular Housekeeping Fuels Brain Disease Through a Viral Alarm System
A new review in the Journal of Translational Medicine details how impaired mitophagy allows mitochondrial DNA to trigger cGAS–STING-driven neuroinflammation ...
Tag: Parkinson’s disease
Blood Test Clues: Mitochondrial DNA Distinguishes Parkinson’s From Look-Alike Disorder
A new study finds that whole-blood mitochondrial DNA copy number, but not telomere length, clearly distinguishes Parkinson's disease from multiple ...
Immune Fingerprints in Blood Reveal Parkinson’s Disease When Patients Are Sorted First
By stratifying Parkinson's patients into mouse-model-anchored immune subtypes, researchers have built T-cell receptor blood tests that exceed 0.8 AUC, overturning ...
Blood Test Combo Flags Who Will Develop Parkinson’s Disease Years Early
A new PPMI analysis shows that combining a blood-based microRNA-7-5p measurement with the alpha-synuclein seed amplification assay can identify prodromal ...
New Algorithm Turns a Classic Math Trick Into a Window on How Disease Rewrites the Way We Walk
A French research team has developed DiaSeg, a framework that extracts diagonal segments from Dynamic Time Warping paths to create ...
Vision Problems May Be the Earliest Warning Sign of Lewy Body Dementia, New Study Finds
Newly designed visual processing tests reveal early dorsal and ventral stream deficits in Lewy body disease that outperform standard cognitive ...
Immune Receptor FcγRIIb Emerges as Gatekeeper of Parkinson’s Protein Spread
New research shows that deleting or blocking the immune receptor FcγRIIb dramatically impairs the spread of alpha-synuclein pathology in the ...
Sleep Drugs Help Parkinson’s Patients Rest Better, But Only One Symptom Shows Solid Benefit
A meta-analysis of 29 randomised trials finds that drugs including melatonin and rotigotine significantly improve overall sleep quality in Parkinson's ...
Antidepressants May Blur the Warning Sign Hidden in Dream-Enacting Sleep
A new letter in the Journal of Clinical Sleep Medicine argues that REM sleep without atonia in people taking antidepressants ...
How Everyday Pollutants Are Quietly Rewiring the Vertebrate Brain
A comprehensive new review reveals how heavy metals, pesticides, industrial chemicals, and air pollutants disrupt neurotransmission, drive neuroinflammation, and threaten ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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