Male mice hit harder by Parkinson’s-linked depression in new study
In an MPTP mouse model of Parkinson's disease, males developed stronger depressive- and anxiety-like behaviors alongside greater nigrostriatal degeneration, hippocampal ...
Tag: Parkinson’s disease
HDAC isoform targeting offers a precision route to treating neurodegeneration
A new review argues that disease-specific HDAC isoforms, not broad-spectrum inhibition, should guide epigenetic drug development for neurodegenerative diseases.
MRI Study Links Blood-Brain Barrier Leaks to Parkinson’s Disease
An exploratory MRI study found widespread blood-brain barrier permeability changes and altered choroid plexus contrast kinetics in patients with Parkinson's ...
NF-κB1 Emerges as a Context-Dependent Switch in Neurodegenerative Disease
A new review argues that the NF-κB1 subunit's p105 and p50 proteins act as context-dependent regulators of neuronal survival and ...
Brain scans reveal cortical thinning and rewired signaling in Parkinson’s disease
A combined structural and functional MRI study of 62 Parkinson's disease patients found cortical thinning in frontal and motor regions ...
Blood Flow in the Parkinson’s Brain Stays Stable Over Two Years Even as Dopamine Markers Decline
PET imaging shows reduced striatal and occipital blood flow in Parkinson's disease that remains stable over two years despite ongoing ...
Parkinson’s Disease Raises Fracture Risk, and Osteoporosis Care Must Keep Up
A new perspective article argues that osteoporosis prevention deserves far more attention in people with Parkinson's disease, especially when dementia ...
Astrocyte-Derived Peptide Analog Shields Dopaminergic Neurons in Parkinson’s Mouse Model
A single intracerebroventricular dose of the ODN analog OP preserved tyrosine hydroxylase-positive neurons and reduced oxidative stress, inflammation, and miRNA ...
Chemometric Tools Sharpen Analysis of Levodopa and Dopamine Across Complex Matrices
A new review maps how chemometric methods paired with spectroscopic, voltammetric, and chromatographic techniques are improving the simultaneous analysis of ...
Asthma Drug Montelukast Shields Nerve Cells from Parkinson-Like Damage in Lab Study
A new cell study reports that montelukast, a common asthma medication, protected human neuroblastoma cells from rotenone-induced toxicity by modulating ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!