Aging Cells Fail at the Final Step of Cellular Recycling, Study Finds
A new study of human skin fibroblasts from donors aged 20 to 96 shows that autophagy's early stages remain intact ...
Tag: p62
Cellular Recycling Machine Linked to Male Fertility Hormone Control
New research reveals that the cellular recycling protein p97/VCP directly regulates the autophagic degradation of androgen-binding protein in Sertoli cells, ...
E3 Ligase TRIM37 Steers Cilia Growth by Tagging p62 and Tuning Autophagy
A new study reveals that the E3 ubiquitin ligase TRIM37 regulates primary cilium assembly by ubiquitinating the autophagy receptor p62 ...
Hidden RNA Switches That Sculpt the Human Fetal Gut Revealed in New Timeline of Autophagy
A new genomic study maps the dynamic expression of autophagy-related circular and long noncoding RNAs across early human fetal intestinal ...
A single ubiquitin enzyme emerges as a master switch between liver repair and liver destruction in MASH
Researchers report that loss of the K63-linked ubiquitination enzyme UBE2N in hepatocytes drives metabolic dysfunction-associated steatohepatitis by blocking p62-mediated mitophagy ...
Ubiquitin Enzyme UBE2N Emerges as Master Switch Between Liver Repair and Damage
A new Nature Metabolism study identifies the ubiquitin-conjugating enzyme UBE2N as the molecular switch that determines whether hepatocytes undergo protective ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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