Researchers have identified a regulatory axis in triple-negative breast cancer where P300 acetylates sclerostin to facilitate its interaction with LRRC15, ...
A scientific review details how lactate metabolism drives cancer epigenetic remodeling, influencing DNA methylation, histone lactylation, RNA modifications, and chromatin ...
Researchers developed domain-alteration chimeras that bind two cooperating proteins to suppress prostate cancer tumors in preclinical models while sparing normal ...
A new hypothesis in Clinical Epigenetics proposes that histone lactylation acts as an epigenetic memory code, linking metabolic reprogramming to ...
A commentary in EMBO Molecular Medicine reviews lysine pyruvylation, a protein modification that links pyruvate metabolism to immune signaling and ...
A randomized, double-blind crossover study in 40 healthy adults found that a single session of bilateral parietal tRNS shortened reaction ...
A single Transformer-based decoder trained on the OpenBMI dataset classified eight EEG classes spanning motor imagery, P300, and SSVEP paradigms ...
A study identifies an SP1/P300/TRAF3IP3 signaling axis that links promoter-specific chromatin remodeling to persistent ERK activation in glioblastoma.
A phase 1 trial found that intranasal creatine prodrug CBT101 was tolerated and produced exploratory EEG changes consistent with central ...
Experimental p300 inhibition reduced breast cancer cell survival and spread, while cytoplasmic localization in patient tumors was associated with lower ...
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