Two Coumarins From Korean Angelica Root Carry Most of Its Anti-Inflammatory Power
A new study shows that the two pyranocoumarins decursin and decursinol angelate reproduce the major anti-inflammatory and antioxidant effects of ...
Tag: NLRP3 inflammasome
Ancient Herbal Medicine Emerges as a Multi-Target Weapon Against Alzheimer’s Disease
A new review maps how traditional Chinese medicine compounds simultaneously target seven core Alzheimer's disease mechanisms through a hierarchical network ...
MitoQ: The Mitochondria-Targeted Antioxidant That Could Slow Aging
A new GeroScience review synthesizes preclinical and human evidence showing that MitoQ, a mitochondria-targeted antioxidant, may counteract age-related cardiovascular, neuronal, ...
Chromatin protein CBX3 emerges as a promising biomarker for cardiovascular disease
A new review highlights how the chromatin protein CBX3 regulates vascular smooth muscle behavior, inflammation, and cancer-related pathways, positioning it ...
Inflammatory Cell Death Emerges as a Driver of Ovarian Dysfunction and Infertility
A new review in Reproductive Sciences details how the inflammatory cell death pathway pyroptosis drives ovarian dysfunction and infertility, and ...
Zinc-Myricetin Nanoshell Rewires Mitochondria and Immunity to Repair Spinal Cord Injury
A lesion-responsive core-shell nanoparticle combining astaxanthin, a ZIF-8 framework, and a zinc-myricetin shell remodels mitochondrial and immune signaling to promote ...
Rapamycin Nanoparticles Rejuvenate Aging Spine Discs by Silencing a Cellular Aging Switch
Rapamycin-loaded nanoliposomes inhibited mTORC1-driven senescence in rat disc cells and slowed intervertebral disc degeneration in vivo, pointing toward an injectable ...
Plant Compound Monotropein Shows Promise Against Stroke Damage by Taming a Key Inflammasome
A new rat study finds that monotropein, a compound from the medicinal plant Morinda officinalis, protects the brain from ischemia/reperfusion ...
Common ‘Forever Chemical’ PFNA Found to Ignite Gut Inflammation at Tiny Doses
New research shows that low-dose exposure to the forever chemical PFNA worsens intestinal inflammation by activating a caspase-11-dependent NLRP3 inflammasome ...
Cell Study Reveals How TRIM28 Fires Up Inflammatory Macrophages to Drive Keratinocyte Overgrowth
New laboratory research shows that the protein TRIM28 drives macrophages toward a pro-inflammatory state through the NLRP3/SGT1 axis and SUMOylation, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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