Broken Cellular Recycling Plants Emerge as Common Thread in Neurodegenerative Disease
A new review in Nature Reviews Neurology argues that defective lysosomal function is a central, genetically validated driver of Parkinson ...
Tag: neurodegeneration
Delayed Visual Signals in the Eye Track Hidden Brain Shrinkage in Multiple Sclerosis
A new study finds that slowed visual evoked potential latencies independently predict brain atrophy and lesion burden on MRI in ...
Immune Receptor FcγRIIb Emerges as Gatekeeper of Parkinson’s Protein Spread
New research shows that deleting or blocking the immune receptor FcγRIIb dramatically impairs the spread of alpha-synuclein pathology in the ...
Stem Cell Transplant Cured a Girl’s Leukemia but Left Her Friedreich Ataxia Unchanged
A decade-long case report shows that allogeneic stem cell transplantation cured a Friedreich's ataxia patient's leukemia and normalized her blood ...
Antidepressants May Blur the Warning Sign Hidden in Dream-Enacting Sleep
A new letter in the Journal of Clinical Sleep Medicine argues that REM sleep without atonia in people taking antidepressants ...
MicroRNA miR-196a Clears Toxic Huntington’s Protein Clumps by Suppressing Rad23b
New research shows that the microRNA miR-196a clears toxic mutant huntingtin aggregates in Huntington's disease by suppressing Rad23b, a ubiquitin ...
Brain’s Waste-Clearance System Emerges as New Alzheimer’s Treatment Frontier
A comprehensive review in Aging Cell details how the brain's glymphatic system and meningeal lymphatic vessels govern Alzheimer's pathology and ...
Polyamine Metabolism Emerges as a Central Player in Neurological Disease
A new review links dysregulated polyamine metabolism to Alzheimer's, Parkinson's, ALS, and other neurological disorders, outlining molecular mechanisms and emerging ...
New PET Tracer Candidate Flags Alpha-Synuclein in Lewy Body Disease But Misses MSA
A new tritium-labeled alpha-synuclein PET ligand, ³H-M503-1619, binds pathological aggregates in postmortem tissue from Lewy body diseases but not in ...
Managing the mental state may ease anxiety-related freezing of gait in Parkinson’s
A randomized controlled trial in npj Parkinson's Disease tested whether strategies for managing anxiety and the mental state can reduce ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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