Sleep loss after brain injury boosts early Alzheimer-like protein changes in mice
A new mouse study shows that traumatic brain injury alone triggers early Alzheimer-like protein variant buildup in wild-type animals, and ...
Tag: neurodegeneration
Hidden Enzymes That Erase Protein Palmitoylation Emerge as Disease Drivers
A new review maps how ABHD enzymes regulate the reversible lipid modification S-palmitoylation and shape cancer, neurodegeneration, antiviral immunity and ...
CSF GFAP Rises Sharply With Age, New Reference Limits Show
A cross-sectional study of 325 screened Danish biobank participants establishes age-specific upper reference limits for Simoa-measured CSF GFAP, which rise ...
Proximity Labeling Maps the Protein Neighborhoods of Two Amyloid Forms in Alzheimer’s Hippocampus
Proximity labeling in postmortem human hippocampus reveals that pyroglutamate-modified Aβ carries an expanded, variant-specific set of neighboring proteins in Alzheimer's ...
Retina’s Master Support Cells Take Center Stage in Blinding Disease
A new review argues that Müller glia, the retina's dominant support cells, actively shape retinal disease progression and may offer ...
People with Parkinson’s disease still read emotions from the way others walk
A study of 38 people with Parkinson's disease and 38 matched controls found that emotion recognition and valence ratings from ...
tRNA Fragments May Link Chronic Stress to Translation Failure in Alzheimer’s Disease
A new review proposes that tRNA-derived small RNAs link chronic cellular stress to maladaptive translational remodeling in Alzheimer's disease.
SAT1 Overexpression Eases Alpha-Synuclein Toxicity in Fly Model of Parkinson’s Disease
In a Drosophila model of Parkinson's disease, neuronal overexpression of the polyamine enzyme SAT1 reduced alpha-synuclein protein levels, modified stress-response ...
Cellular Stress Protein JWA Emerges as Context-Dependent Redox Hub in Aging and Disease
A new narrative review synthesizes how the multifunctional protein JWA intersects with redox homeostasis across cancer, neurodegeneration and tissue injury, ...
Peroxisomal Protein PEX11β Restores Mitochondrial Function and Behavior in Huntington’s Disease Mice
Restoring the peroxisomal fission protein PEX11β improved motor and cognitive deficits and mitochondrial gene expression in a toxin-induced mouse model ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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