Hemp Seed Cake Yields Two Natural Molecules That Block a Key Diabetes Enzyme
Scientists isolated two phenylpropionamide compounds from hemp seed cake that inhibit the diabetes-linked enzyme PTP1B in vitro, with kinetic, docking, ...
Tag: network pharmacology
Ancient Chinese Herbal Formulas Show Promise as Multi-Target Anti-Aging Therapies
A sweeping review maps classical Chinese medicine formulas onto the fourteen hallmarks of aging, revealing multi-target molecular mechanisms and clinical ...
Common Cosmetic Preservative Methylparaben Linked to Breast Cancer Mechanisms in Landmark Computational Study
A new computational study links the common cosmetic preservative methylparaben to five key breast cancer signaling proteins and unveils a ...
Icariin Targets NOX4 Oxidative Stress Hub in Gastric Cancer, Multi-Omics Study Finds
An integrated multi-omics and single-cell study identifies the ROS-generating enzyme NOX4 as a candidate target through which the Epimedium-derived flavonoid ...
Atomic-Scale Toolkit Reveals How Ancient Herbal Formulas Hit Multiple Targets at Once
A new review details how cryo-electron microscopy, AI modeling and time-resolved crystallography are decoding the multi-target synergy of traditional Chinese ...
Toad Venom Compound Bufalin Blocks Melanoma Growth by Switching Off AKT Signaling
New research shows that bufalin, a steroid from traditional Chinese toad venom, suppresses melanoma growth, metastasis and angiogenesis by reducing ...
Tea Compounds Show Surprising Power Against Cancer and Aging Proteins
A new network pharmacology study identifies 14 tea phytochemicals that strongly bind the cancer- and metabolism-linked hub proteins PIK3CA, AKT1, ...
Zerumbone Shows Promise Against Cervical Cancer by Disrupting IL-10 Immune Signaling
A new study combines computational modeling and cell-based experiments to show that the plant compound zerumbone suppresses IL-10–driven JAK–STAT signaling ...
Ancient Chinese Herbal Formula Restores Skin Barrier in Eczema by Switching On a Key Repair Pathway
A clinical trial and a series of animal and cell experiments show that the traditional Chinese formula gu-ben-hua-shi repairs the ...
Common Medicinal Plant Shows Promise Against Cobra Venom in New Study
A hydromethanolic extract of Plumbago zeylanica aerial parts inhibited key cobra venom enzymes, prolonged survival in envenomated mice and showed ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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