Computational Map Splits Atropine’s Myopia Targets From Dry Eye Pathways
A computational study identified 57 shared and 19 myopia-specific atropine targets, linking inflammatory remodelling pathways to both myopia control and ...
Tag: network pharmacology
Traditional Chinese Formula Zhizhu Decoction Eases IBS-Like Symptoms in Rats
A network pharmacology and rat study found that the traditional Chinese formula Zhizhu Decoction improved constipation-predominant IBS-like symptoms, intestinal barrier ...
Yeast fermentation products rank first for boosting feed intake in cattle
A network meta-analysis ranked Saccharomyces cerevisiae fermentation products first among 22 interventions for increasing dry matter intake in cattle, with ...
Computational Design Yields Four Hydrazone Candidates Against Gastric Cancer Cells
An entirely computational study designed four hydrazide–hydrazone candidates with predicted activity against the MGC803 gastric cancer cell line and prioritized ...
Traditional Chinese Medicine Compounds Trigger Cancer Cell Ferroptosis via TP53
Researchers report that ursolic acid and Anhydroicaritin, key components of the traditional formula Fuzheng Yiai, bind and upregulate TP53 to ...
Juniper extract nanoparticles show antimicrobial and anticancer activity in lab tests
Egyptian researchers loaded Juniperus phoenicea leaf extract into nanostructured lipid carriers that showed enhanced antibacterial activity against Acinetobacter baumannii and ...
Two Collagen Peptides from Pig Skin Shield Skin Cells from UV Damage
Researchers identified two porcine skin collagen peptides, FGPYGF and GPPSGGFG, that protected UVB-damaged human keratinocytes in cell culture by acting ...
Kaempferol Eases Muscle Wasting in Mice With Cancer Cachexia
A study combining bibliometric mining, network pharmacology and mouse experiments identified the plant flavonoid kaempferol as a candidate compound against ...
Pinocembrin Shows Dual Kidney Protection in Diabetic Mouse and Cell Models
A new study reports that the propolis-derived flavonoid pinocembrin reduced kidney injury in diabetic db/db mice and high-glucose-treated kidney cells ...
Research report: Ambrisentan ameliorates methotrexate nephrotoxicity through modulation of RhoA/ROCK and PI3K/MDM2-associated signaling: network pharmacology-guided discovery and in vivo confirmation
A rat study found that the pulmonary hypertension drug ambrisentan, given before and during methotrexate exposure, protected the kidneys by ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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