‘Hard to lose’ mutations in tumors may predict response to immunotherapy
Cancer experts have tried, sometimes unsuccessfully, to use the total number of mutations in a tumor, called the tumor mutation ...
Tag: mutations
AI analysis of cancer mutations may improve therapy
Cancer has many faces – no wonder, then, that the range of cancer-causing mutations is huge as well. The totality ...
Polygamous birds have fewer harmful mutations
Bird species that breed with several sexual partners have fewer harmful mutations, according to a study led by the Milner ...
MD Anderson EGFR Classification licensed by BostonGene and Tempus to provide new insight on atypical mutations in lung cancer
HOUSTON ― The University of Texas MD Anderson Cancer Center today announced licensing agreements with BostonGene Corporation and Tempus for ...
Oncoscience | Association between tumor mutations and meningioma recurrence in Grade I/II disease
“Though meningioma patients often see favorable oncological outcomes, many tumors still recur post-surgically.” Credit: 2022 Dullea et al. “Though meningioma ...
In cells, UV-emitting nail polish dryers damage DNA and cause mutations
The ultraviolet nail polish drying devices used to cure gel manicures may pose more of a public health concern than ...
Unlocking how mutations help pancreatic cancer grow
Only about 11% of people will survive five years after the detection of advanced pancreatic cancer. Such a low rate ...
New computer program ‘learns’ to identify mosaic mutations that cause disease
Genetic mutations cause hundreds of unsolved and untreatable disorders. Among them, DNA mutations in a small percentage of cells, called ...
Why synonymous mutations are not always silent
New modeling shows how synonymous mutations—those that change the DNA sequence of a gene but not the sequence of the ...
Specific modifier genes determine the effect of mutations that cause non-compaction cardiomyopathy
Non-compaction cardiomyopathy is a heart condition caused by defects that arise during fetal development and can have diverse health impacts ...
Monkeypox mutations cause virus to spread rapidly, evade drugs and vaccines, MU study finds
COLUMBIA, Mo. – Monkeypox has infected more than 77,000 people in more than 100 countries worldwide, and — similar to ...
Dartmouth study offers new insights into genetic mutations in autism disorders and points to possible treatments
Findings from a new study published in Cell Reports, involving a collaborative effort between researchers at the Luikart Laboratory at Dartmouth’s Geisel School of Medicine ...
Anti-cancer drugs, olaparib and adavosertib, work best when given sequentially in patients with advanced tumours driven by DNA damage response mutations: results from Phase Ib STAR clinical trial
Barcelona, Spain: Patients with cancers that are driven by certain mutations occurring in response to DNA damage can be safely ...
AKT inhibitor shows signs of effectiveness in a patient trial matching drugs to tumour gene mutations
NB: this presentation will be the subject of an embargoed news briefing by co-author Dr Kevin Kalinsky on Monday 24 ...
Investigating rare genetic mutations led Pitt scientists to surprising blood pressure discovery
PITTSBURGH, Oct. 4, 2022 – The kidneys are often the unsung heroes in maintaining healthy blood pressure, filtering 180 liters ...
NIH-funded team develops method to identify future SARS-CoV-2 mutations that could affect rapid antigen test performance
A research team funded by the National Institutes of Health has shown that commercially available rapid antigen tests can detect ...
Story tips: Inland water carbon emissions on the rise, sealed with silica, cancer-fighting chemistry, improving materials for energy storage, using math to predict SARS-CoV-2 protein mutations
Inland water carbon emissions on the rise Analysis points to land use, climate events Credit: Adam Malin/ORNL, U.S. Dept. of ...
Corals pass mutations acquired during their lifetimes to offspring
In a discovery that challenges over a century of evolutionary conventional wisdom, corals have been shown to pass somatic mutations ...
Researchers find spaceflight may be associated with DNA mutations and increased risk of developing heart disease and cancer
Astronauts are at higher risk for developing mutations—possibly linked to spaceflight—that can increase the risk of developing cancer and heart ...
Singapore scientists develop AI-based method to identify cancer mutations
Scientists from A*STAR’s Genome Institute of Singapore (GIS) have developed a novel artificial intelligence (AI)-based method, named Variant Network (VarNet), ...