RNA-Binding Protein ADAR2 Throttles Bladder Cancer Spread by Destroying Fat-Making Enzyme Message
A new study shows that the RNA-binding protein ADAR2 suppresses bladder cancer metastasis by destabilizing FASN mRNA and curbing fatty ...
Tag: mRNA stability
Estrogen receptor fuels breast cancer growth through an RNA-tagging loop, study finds
New research reveals that estrogen receptor alpha drives an m6A-dependent RNA stabilization pathway through HNRNPC and DDX6 that promotes the ...
RNA-Binding Protein PTBP3 Drives Kidney Scarring in Diabetes, Study Finds
Researchers at Harbin Medical University report that the RNA-binding protein PTBP3 stabilizes SMAD3 mRNA and drives podocyte epithelial-to-mesenchymal transition, and ...
Silent No More: Hidden PROS1 Mutations Drive Dangerous Blood Clotting Disorder
A new study shows that synonymous PROS1 variants once considered harmless can cause Protein S deficiency through aberrant splicing and ...
RNA Chemical Tag Drives Endometrial Cancer Through a DNA Repair Protein, Study Finds
New research reveals that the RNA modification reader ALYREF drives endometrial cancer progression by stabilizing XRCC6 mRNA and activating Wnt/β-catenin ...
Codon Optimality Predicts mRNA Lifespan but Fails for Noncoding RNAs
A new computational study shows that codon optimality, one of the strongest sequence determinants of messenger RNA half-life, does not ...
Hidden RNA Tag Drives Paclitaxel Resistance in Bladder Cancer, Study Finds
Researchers report that the RNA-binding protein IGF2BP3 stabilizes m6A-tagged CENPA mRNA to fuel paclitaxel resistance in bladder urothelial carcinoma, identifying ...
TDP-43 Loss Triggers Broad Polyadenylation Shifts in FTD/ALS
In a groundbreaking study published in Nature Neuroscience, researchers have unveiled that the nuclear depletion of the protein TDP-43 in ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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