Mouse Models Show Teeth Can Expose Hidden Signs of Rare Bone Disease
New knock-in mouse models of hypophosphatasia show that specific ALPL gene variants shape dental symptoms independently of blood enzyme levels, ...
Tag: mouse models
Immune Fingerprints in Blood Reveal Parkinson’s Disease When Patients Are Sorted First
By stratifying Parkinson's patients into mouse-model-anchored immune subtypes, researchers have built T-cell receptor blood tests that exceed 0.8 AUC, overturning ...
Blocking the Growth Hormone Receptor Extends Mouse Lifespan, Landmark Study Finds
A formal aging study of 351 mice shows for the first time that blocking the growth hormone receptor with an ...
Head-Fixed Mice Learn to Self-Administer Drugs, Opening a New Window on Addiction
A new Nature Protocols article details how to combine head fixation with intravenous drug self-administration in mice, uniting voluntary drug-taking ...
Gut Oxygen Sensor Shields Against Obesity but Adds Nothing to Weight-Loss Surgery
New mouse research shows intestinal HIF1α is unnecessary for the metabolic gains of bariatric surgery but plays a vital protective ...
Scientists Map the Hidden Cellular Matrix Landscapes That Drive Allergic Airway Inflammation
A new imaging mass cytometry pipeline reveals region-specific extracellular matrix environments that shape immune cell behaviour during allergic airway inflammation ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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