Tag: Morris water maze

Acarbose, a well-established medication recognized for extending lifespan in laboratory animals, successfully prevented age-related spatial memory loss in a genetically ...

Researchers have discovered that cytosolic HDAC7 non-enzymatically bridges tau and GSK3β, driving kinase activation, tau hyperphosphorylation, and cognitive impairment in ...

Engineered chiral gold nanozymes anchored to Faecalibacterium duncaniae protected the anaerobic probiotic, reversed diet-induced steatohepatitis lesions, and mitigated secondary cognitive ...

A narrative review evaluates behavioral testing paradigms across rodents, tree shrews, pigs, dogs, and non-human primates to clarify translational capabilities ...

Researchers synthesized novel benzothiazole-linked diazepino derivatives that inhibited acetylcholinesterase and significantly reduced escape latency in a scopolamine-induced rat model of ...

A rat study reveals that lead exposure triggers microglial iNOS upregulation, depressing SNARE-regulating proteins and impairing hippocampal synaptic plasticity.

Researchers found that ethanol extracts and flavone glycosides from Dicliptera chinensis reduced cellular senescence markers in neuroblastoma cells and improved ...

Icariin, the main bioactive component of Herba Epimedii, reversed nucleolar stress markers in Aβ25–35-treated BV2 cells and APP/PS1 mice, according ...

A mouse study finds that inhibiting the NLRP3 inflammasome specifically in microglia reduces hippocampal neuroinflammation and reverses cognitive deficits after ...

A mouse study finds that age- and diet-dependent changes in astrocyte complexity within the hippocampal temporoammonic pathway parallel spatial learning ...