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First Human Dosimetry Study Validates Radiation Profile of Astrogliosis PET Tracer [18F]SMBT-1
A human clinical trial reveals that the reactive astrogliosis PET tracer SMBT-1 displays an effective radiation dose comparable to established ...
Tag: monoamine oxidase-B
Selegiline shields mouse memory from repeated anesthesia damage
Repeated isoflurane exposure impaired memory and hippocampal CA1 function in mice, and pretreatment with the approved drug selegiline prevented most ...
First Immune-Modulating Drug Trial Targets Neuroinflammation in Prodromal Parkinson’s Disease
A published protocol details the first randomised, placebo-controlled trial testing whether the oral drug PXS-4728A reduces PET-measured brain neuroinflammation in ...
Theobromine Shows Parkinson’s Promise, but Human Evidence Remains Thin
Biochemical and animal studies suggest that cocoa-derived theobromine can affect monoamine oxidase, adenosine and neuronal signaling, but no clinical evidence ...
Butterfly-Shaped Coumarin Molecules Show Promise as Dual Alzheimer’s Enzyme Blockers
New halogenated bis-coumarin compounds inhibit both acetylcholinesterase and monoamine oxidase-B at micromolar concentrations, offering a dual-target template for Alzheimer's drug ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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