SADRP: A structurally aware multi-modal framework for drug response prediction
SADRP combines drug topology, chemical-bond information, gene expression and DNA methylation to predict drug sensitivity across cancer cell lines.
Tag: molecular structure
Hidden Electron Donors Steer the Molecular Architecture of Propylene–Ethylene Copolymers
A new study shows that the internal electron donor in titanium–magnesium Ziegler–Natta catalysts controls how ethylene units are sequenced in ...
Cryo-EM Reveals How Cas12a Uses a DNA Guide to Hunt RNA Targets
A new cryo-EM structure of Acidaminococcus sp. Cas12a reveals how the enzyme uses a DNA guide and structural mimicry to ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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