Candidate Genes Link Polymer Degradation Products to Myeloma Prognosis and Immune Heterogeneity
A bioinformatic and preliminary experimental study identifies PTGS1, CA1, and SYK as prognostic genes in multiple myeloma and explores, without ...
Tag: molecular docking
Homozygous GUCY2D Variant Linked to Blindness in Iranian Family
An Iranian study reports an independent observation of a homozygous GUCY2D variant in a patient with Leber congenital amaurosis, supported ...
New Indole–Benzimidazole Hybrids Built Through Optimized Multistep Synthesis
Chemists report a scalable multistep synthesis of indole–benzimidazole–piperazine carboxamide hybrids, optimized bond by bond and computationally profiled without claims of ...
Computational models point to pleconaril derivatives as candidate antienteroviral agents
A computational study of twenty-four novel pleconaril derivatives identifies molecule 12b as the strongest binder to the enterovirus D68 capsid ...
Natural Saponin Esculentoside A Curbs Liver Cancer Growth by Stabilizing RORB Protein
A new preclinical study reports that the plant-derived saponin esculentoside A suppresses hepatocellular carcinoma growth and stemness in cells and ...
Genetic study links gut microbes to ulcerative colitis and flags two biomarkers
A Mendelian randomization and transcriptomic study identified 11 gut microbial taxa genetically associated with ulcerative colitis and nominated PHLPP2 and ...
Computational study links PCB118 to estrogen receptor ESR1 in breast cancer
A computational network toxicology and molecular docking study predicts a theoretical interaction between the pollutant PCB118 and the estrogen receptor ...
Soft Fish Protein Gels Built from Interlocking Molecular Networks
Researchers built a soft, water-rich edible gel by interpenetrating a calcium-crosslinked sodium alginate network with an ovalbumin-modified silver carp myofibrillar ...
Genetic Study Links Specific Blood Lipids to Pre-eclampsia and Eclampsia Risk
A Mendelian randomization study of 179 plasma lipids identifies triacylglycerol (50:1) as a genetically associated risk factor for pre-eclampsia, eclampsia, ...
PET Microplastics Linked to Pregnancy Loss Mechanisms in Exploratory Study
An exploratory study links PET microplastic exposure to immune and signaling changes in recurrent pregnancy loss, identifying YWHAZ as a ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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