Cancer Cells Run on a Metabolic Hybrid Engine, and Surgeons May Soon Map It
A new review argues that cancer cells toggle between glycolysis and mitochondrial respiration in hybrid metabolic states, and that mapping ...
Tag: mitochondrial DNA
Hidden Frog Diversity in Yunnan: DNA Study Collapses Two Species and Extends Another’s Range
A new genetic and morphological study of torrent frogs in southern Yunnan reveals that two recently named species are junior ...
Decades-old formalin museum insects surrender their mitochondrial DNA
Natural history museums have long been treasure houses for evolutionary research, but one of their most common preservation methods has ...
Mosquito Genes Map Colombia’s Hidden Aedes aegypti Lineages
A country-scale mitochondrial study of Aedes aegypti in Colombia reveals two broad genetic clusters shaped by urbanization, history, and climate ...
Single-Cell Sequencing Reveals Mitochondrial DNA Damage in Vulnerable Parkinson’s Neurons
For the first time, researchers have sequenced mitochondrial DNA from individual vulnerable brainstem neurons in Parkinson's disease, revealing extensive deletions ...
Rare Sugar D-Allose Rewires a Mitochondrial Stress Circuit to Slow Disc Degeneration
A new study shows that the rare sugar D-allose restores mitophagy, suppresses cGAS–STING signalling and preserves the cytoprotective peptide ADM2 ...
How Failing Mitochondria Turn Cells Into Engines of Ageing Inflammation
A new GeroScience review details how failing mitochondria act as both initiators and amplifiers of cellular senescence and the chronic ...
Genetic Sleuthing Confirms the Mysterious Tibetan Brown Bear Roams Nepal’s High Deserts
The first genetic confirmation of the Tibetan brown bear in Nepal resolves a long-standing subspecies mystery and provides a critical ...
Bacterial Toxin Hijacks Mitochondria to Trigger Fatal Cell Death in Bovine Mastitis
New research reveals that the Staphylococcus aureus virulence factor Sph disrupts mitochondrial cristae through Mic60, releasing mtDNA that activates the ...
Long-Read Sequencing Achieves Near-Perfect Detection of Mitochondrial DNA Variants Linked to Parkinson’s Disease
A validated PacBio HiFi long-read sequencing workflow detects low-frequency mitochondrial DNA heteroplasmy with near-perfect accuracy and reveals dynamic variant trajectories ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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