Designed From Scratch: Microproteins Take Aim at Brain Disease
De novo designed microproteins, built computationally to bind toxic amyloid fibrils and restore mitochondrial function, are emerging as promising candidates ...
Tag: microproteins
Cancer’s Hidden Proteome: Thousands of Dark Proteins Emerge as Drug Targets
A landmark Perspective in Nature Reviews Cancer argues that the cancer dark proteome — thousands of uncharacterized proteins from non-canonical ...
Hidden Genome: Tiny Proteins Mapped Across the Parasite Behind Trichomoniasis
Researchers have built the first comprehensive atlas of 918 microprotein candidates in Trichomonas vaginalis, confirming translation of 103 of them ...
Tiny but mighty: microproteins emerge as regulators of disease and future precision therapeutics
A new review in 3 Biotech charts how tiny proteins encoded by small open reading frames regulate cancer, heart disease, ...
Hidden Microproteins in the Aging Brain Could Reshape Alzheimer’s Research
An atlas of the aged human brain catalogs over 1,000 high-confidence microproteins, including an MKKS-encoded microprotein reduced in Alzheimer's disease ...
Hidden Microproteins in the Human Brain Map a New Frontier of Alzheimer’s Disease
A new atlas catalogues 1,067 unannotated microproteins in the human frontal cortex and reveals that a subset, including an MKKS-derived ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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