Hidden RNA Molecule Drives Ovarian Cancer Growth by Activating Key Stress Pathway
Researchers found that the long non-coding RNA ATP6V1B1-AS1 promotes ovarian cancer growth and metastasis by binding MAP3K3 and activating the ...
Tag: metastasis
Liposomal Quercetin Blocks Lung Cancer Spread in Mice, With Liquid Biopsies Tracking Every Step
Liposome-encapsulated quercetin completely suppressed liver metastasis in a mouse model of lung cancer while liquid biopsy cell analysis and ex ...
Two Molecular Machines, One Cancer Engine: How Deubiquitinases and m6A RNA Tags Talk to Each Other
A new review in Molecular Cancer maps the bidirectional crosstalk between deubiquitinases and m6A RNA modification, revealing a coupled regulatory ...
Single-cell atlas reveals how hidden clones drive pancreatic cancer’s deadly evolution
A landmark single-cell and spatial transcriptomics study of 62 pancreatic tumors shows that genetically distinct clones within each cancer drive ...
Pancreatic Cancer Cells Constantly Rewrite Their DNA to Outsmart Treatment
A single-cell analysis of nearly half a million pancreatic cancer cells shows that continuously evolving clones reshape their DNA to ...
Cellular Stress Hubs Help Oral Cancer Spread, Study Finds
New research shows that stress-induced eIF2α phosphorylation drives stress granule formation that promotes growth and metastasis in oral squamous cell ...
Melanoma’s Deadly Shift: DNA Methylation Rewrites the Tumor as It Spreads
A paired-sample study of 38 melanoma patients reveals that metastases undergo coordinated DNA methylation reprogramming largely independent of driver mutations, ...
Sepsis May Leave Tissues Primed for Cancer, Review Argues
A new review in the Journal of Translational Medicine argues that sepsis may remodel tissues through an Immuno–Vascular–Matrix Triad in ...
Modified Acupuncture Needle Offers Minimally Invasive Route to Lymph Node Molecular Profiling
Researchers have re-engineered an acupuncture needle into a minimally invasive device that samples DNA biomarkers directly from lymph nodes for ...
Experimental Drug SMIP004 Hunts Down Dormant Cancer Cells Left Behind by Chemotherapy
Researchers report that the mitochondria-targeting compound SMIP004 selectively kills therapy-induced senescent cancer cells by promoting degradation of the AMPK-stabilized metabolic ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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