Fumarate Impairs DNA Repair in Kidney Cancer Cells
A new study reveals that fumarate accumulation in kidney cancer cells impairs DNA repair by modifying the RPA1 protein, leading ...
Tag: metabolic reprogramming
BCAT1 Suppresses Pancreatic Cancer by Degrading SLC3A2
A new study reveals that BCAT1 acts as a tumor suppressor in pancreatic adenocarcinoma by promoting the BTRC-dependent degradation of ...
DNMT3B Drives Lung Cancer Glycolysis by Silencing TAL1
A study in Cell Division reveals that DNMT3B promotes non-small cell lung cancer progression by methylating TAL1, which leads to ...
Review Outlines Metabolic and Immune Regulatory Networks Driving Gout Inflammation
A scientific review details how the HIF-1α and HK2 metabolic axis regulates the balance between Th17 and regulatory T cells ...
Review Highlights Shared Metabolic Reprogramming in Atherosclerosis and Cancer
A scientific review details shared metabolic reprogramming between atherosclerosis and cancer, establishing a theoretical foundation for potential common therapeutic strategies.
Electric Current Accelerates Microbial Silver Extraction From Discarded Solar Photovoltaic Cells
Applying a ten-milliampere direct current to microbial leaching cultures increases silver extraction from decommissioned photovoltaic cells nearly ninefold by simultaneously ...
Researchers Examine Malate-Aspartate Shuttle in Gastric Atrophy and Precancerous Progression
A scientific review evaluates the malate–aspartate shuttle as a candidate redox–bioenergetic hub in gastric atrophy and precancerous disease progression.
DAPK1–Lipin1 fatty acid oxidation axis exposes ferroptosis vulnerability in colorectal cancer
Researchers found that the kinase DAPK1 stabilizes Lipin1 to boost fatty acid oxidation, raising lipid peroxidation and making colorectal cancer ...
How HPV rewires sugar chemistry in cervical cancer cells
A new review finds that O-GlcNAcylation links HPV-driven metabolic demand to growth and survival pathways in cervical cancer, but no ...
Review Explores Metabolic Reprogramming of Regulatory T Cells in Colorectal Cancer
A review in the Journal of Translational Medicine examines how metabolic reprogramming enables regulatory T cells to drive immunosuppression in ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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