Gut hormone GLP-2 reshapes cattle mesenteric blood flow through cholinergic vascular signaling
Glucagon-like peptide 2, better known as GLP-2, has long been celebrated as the gastrointestinal system's own growth serum. Secreted naturally ...
Tag: mechanisms
Hidden Biomechanics of a New Knee Therapy Revealed by Finite Element Simulation
Knee osteoarthritis quietly reshapes the lives of hundreds of millions of older adults, turning simple walks into painful negotiations between ...
How Doxorubicin Hijacks the Heart’s Cellular Cleanup Crew — and Why It Matters
A sweeping review reveals how the chemotherapy drug doxorubicin breaks the heart's mitochondrial and ER recycling systems at multiple checkpoints, ...
Kinase Inhibitors Beat Aggressive Skin T-Cell Lymphomas—Until Tumors Learn to Fight Back
A new review maps how aggressive cutaneous T-cell lymphomas develop resistance to targeted kinase inhibitors, revealing gatekeeper mutations and cross-kinase ...
IL-24 steps out of the shadows as a central regulator of liver disease
A new review in Molecular Biology Reports maps how interleukin-24, once known only as a melanoma differentiation gene, regulates hepatocellular ...
Why Loneliness Follows Parkinson’s Disease: Illness Acceptance and Community Confidence Hold the Key
Parkinson's disease has long been recognized as a disorder of movement, but a growing body of research reveals a quieter, ...
Graphene Oxide and Conductive Polymer Blends Reveal the Hidden Circuitry of Methanol Gas Sensors
A Kirchhoff-based circuit model explains why graphene oxide and PEDOT blends show a resistivity minimum at 78 percent PEDOT but ...
Machine Learning Reveals How Fungicides Bind to Proteins of the Potato Blight Pathogen
A computational study models how the fungicides fluopicolide and propamocarb bind to cytochrome P450 and glutathione-S-transferase proteins of Phytophthora infestans, ...
How Broken Brain Networks and Molecular Chaos Drive Major Depression
A sweeping integrative review argues that major depressive disorder arises from interacting molecular dysregulation and large-scale brain network dysfunction, while ...
Tiny vesicles could offer a drug-free path to treating deadly aortic aneurysms
Abdominal aortic aneurysms, or AAAs, are a silent killer that affects millions worldwide. This bulging of the body's largest artery ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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