Intrathecal Stem Cell Therapy Reshapes CSF Proteins, Not Blood Immune Cells, in Progressive MS Trial
An integrated blood and CSF multi-omics analysis of the SMART-MS randomized trial found that intrathecal mesenchymal stem cell therapy in ...
Tag: mass cytometry
Cysteine Cathepsins Mapped Across Breast Tumors Reveal States That May Shape Antibody-Drug Conjugate Use
A single-cell and spatial atlas of 66 breast tumors shows cysteine cathepsins occupy specific immune, epithelial and stromal niches, and ...
Within 24 Hours, an mRNA Booster Reshapes the Immune System—and Naive CD4 T Cells May Hint at Breakthrough Infection Risk
A new mass cytometry study reveals that mRNA booster vaccination triggers rapid, lineage-specific immune remodeling within 24 hours, with early ...
Cell Cycle Timing Shapes How Natural Killer Cells Fire Their Weapons
A combined CyTOF and computational modeling study shows that NKG2D signaling and degranulation in human NK cells depend on the ...
Conformation-Selective PI3Kδ Inhibitor Roginolisib Shows Safety and Survival Signals in First-in-Human Cancer Trial
A first-in-human trial shows that the conformation-selective PI3Kδ inhibitor roginolisib is well tolerated in advanced cancers and is associated with ...
CytoVI: Deep learning model unifies antibody-based single-cell data across platforms
Researchers have developed CytoVI, an open-source deep generative model that integrates, denoises and imputes antibody-based single-cell data from flow cytometry, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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