AlphaFold 3 Structures Can Guide T-Cell Receptor Engineering, With Caveats
A benchmark of 438 TCR–pMHC mutations shows experimental structures remain the best input for binding-affinity predictors, while AlphaFold 3 mutant ...
Tag: machine learning in immunology
AI Designs Working T-Cell Receptors That Could Transform Immunotherapy Screening
Researchers have developed a transformer-based AI model that generates functional T-cell receptor sequences tailored to specific epitopes, with laboratory tests ...
Proximity-guided graph learning reveals tumour-associated proximity antigens
The concept of a proximity antigen sits at an important intersection of tumour immunology, spatial biology, and machine learning, and ...
New AI Tool Identifies Proinflammatory Peptides Using Phase-Based Descriptors and Self-Attention
Inflammation is one of the body’s most powerful protective responses, but when it becomes excessive or misdirected, it can contribute ...
UTMB Scientists Leverage AI to Develop Next-Generation Vaccines Against Emerging Alphaviruses
A team of researchers at The University of Texas Medical Branch (UTMB), spearheaded by Dr. Nikos Vasilakis and Dr. Peter ...
PredIG: A Clear Predictor for T-Cell Epitope Immunogenicity
In a groundbreaking study, researchers have unveiled PredIG, a state-of-the-art computational tool designed to predict the immunogenicity of T-cell epitopes. ...
Machine Learning Transforms B-Cell Epitope Prediction
In the rapidly evolving landscape of immunology, B-cell epitope prediction has emerged as a crucial focus, particularly with advancements in ...
Revolutionary Immune ‘Fingerprints’ Enhance Complex Disease Diagnosis in Stanford Medicine Research
A groundbreaking advancement in immunology is revolutionizing how we diagnose diseases, potentially transforming the landscape of medical diagnostics. Researchers at ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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